Yeah, just ask Dave Sim ("Wolveroach") and Alan Moore ("Marvelman" renamed MIRACLEMAN) about Marvel's tendencies in that direction.
Disney sued Marvel in 1980-1981 over Howard the Duck, forcing Marvel to put pants on Howard to separate him from Donald Duck. I doubt it makes the slightest diffence to anyone but Disney.
Ignoring that the mouse looks a bit like Mickey (more like Mighty Mouse IMO), they are opening marketing the book with dozens of trademarked MCU and DC characters on it. I can't imagine either company allowing any of them on the cover these days.
