If one looked at the film's ending from an Indie perspective, it was actually pretty decent.
But since they went for this whole Bakersfield survival horror meets Independence Day decorum, the implied 'unique survivor becomes humanity's last best hope' approach felt off kilter for a conclusion.
They could have at least panned out and showed a bunch of other 'glowing red brain' cases surface throughout the world and imply an inevitable uprising.
But hell, at least they didn't end the movie at the point where they were sucked up into the ship. I was scared to death that-that's where it was going to end.