Saturn Ray makes a fair point about my lots. The good stuff which is easy to sell - for example, the complete run of Authority - I started high and made a lot of money out of, when I bought them individually and sold them for double what I paid when Authority mania was at its peak. And, with apologies to Basti, the hardcover Kingdom Come I bought from him I re-sold at a small profit (I really needed the spare cash at the time for X-mas presents!).
But the more difficult stuff is harder - I've been trying to get rid of run of Perez Wonder Woman and all WW tpbs for about a year. I could probably sell them if I dropped the price right down, but its difficult to do that when I'm outside of the US and shipping to the US tends to be so much. I sold a big batch of tpbs to Theo very recently, and said I'd charge him $8 postage when it actually came to $25 - half the purchase price! I couldn't charge anyone that sort of cash for postage - they'd pull out of the deal.
I have a big run of X-men and also Sandman siting in Australia which I'll sell when I get back, and I think I'll follow Basti's advice on not splitting the lots. With X-men its hard to tell, because some bozo will want issue 170 and be willing to buy dog-eared 166 and 168 to get it. Sandman I'll sell as a big lot.
Theo told me something interesting once - he won't bid if there is a reserve price, because he thinks he isn't getting a bargain. I think there is some truth to that - I hate bidding on reserve lots.