Jeez...there are a lot of titles that just blew - though, I'm surprised by one or two of the other comments (love Hitch, loved all of Midnight Nation). Ok, what sucked ass:
Origin - that book sucked on so many levels - the story - boring, the art was so-so...all the hype for nada, squat, zero, zip...
Spiderman: Blue was disappointing.
DKSA for the same reasons as Origin - when is Miller going to do another Sin City tale?
The Batgirl title - not to be confused with the excellent Batgirl: Y1 mind you, but the title does nothing for me - but I admit, I'm also biased, as I really don't like the new BG.