I've been through this so I'll tell you what comics got my wife interested in comics:
Ghost World
Fables: As cheesy as the premise sounds the stories are incredible
The 1st Catwoman Trade with Brubaker and Pulido
Maus
Tom Strong
Once she was into comics I hit her with Swampthing and Sandman and she really liked them, but I would save those for later. I think the best one to start with is Fables, it has alot of characters she allready knows and loves and if you start with the trades it's like she can get in on the ground floor.
