The News Crew Brawl in Anchorman.
Neo vs. 100 Smiths in Matrix Reloaded.
Anakin Skywalker vs. Obi-Wan Kenobi in Revenge of the Sith.
The Bar Brawl in Desperado.
Narrator vs. Angel Face in Fight Club.
Eowyn vs. Witch King in Return of the King. (Short but just too cool!)
Silent Bob vs. Golgothan in Dogma.
Achilles vs. Hector in Troy.
Yoda vs. Emperor Palpatine in Revenge of the Sith.
Qui-Gon Jinn & Obi-Wan Kenobi vs. Darth Maul in The Phantom Menace.
All of Die Hard.
The Tank Fight in Indiana Jones and the Last Crusade.
The Bride vs. Elle Driver in Kill Bill vol. 2.
Wesley vs. Inigo Montoya in The Princess Bride.
Marv vs. Kevin in Sin City.
Samwise Gamgee vs. Shelob in The Two Towers.
Aragorn & Co. vs. Orcs, Mercenaries, and Olliphants (oh, my!) in Return of the King. (That includes the Legolas vs. Olliphant battle.)
That's all I can think of right now. More if I can think of 'em.