1. Hyde rapes and kills the Invisible Man in League of Extraordinary Gentlemen? ("His end...was comfortable.") All we see is blood on Hyde's mouth, Hyde's bare arse, the Invisible Man's screams, and Hyde clearly enjoying himself. Brrr.
2. Apollo is raped by the Commander and Thunder God in Authority #13?
3. Lucifer casually destroys billions of worlds by simply passing through the fragile dimension of the Mansions of Silence in the Vertigo title?
4. The Anti-Monitor kills Supergirl in Crisis on Infinite Earths #7?
5. Dark Phoenix consumes a star and kills 5 billion intelligent beings, in Claremont and Byrne's Dark Pheonix Saga in Uncanny X-men? The first genocide in comics.
6. The Phantom Zone criminals wipe out the bubble universe in Byrne's Superman #22-24, driving Supes to finally take a life?