Here's what I'm interested in when it comes to LOST:
1) Answers and explanations about the Hanso Corporation, The Others, the Dharma Initiative, and the supernatural nature of the island and its monsters.
2) Why Locke was in a wheelchair.
3) Why Desmond can see the future when the writers want him to (notice he didn't see old Eko getting smoked).
4) Walt. Anyone ever going to explain that kid?
5) The overall point/purpose of the show. I swear they're trying to get a message or point across, but, I just can't make it out through all the jumbled storylines and commerical needs of ABC.
What I'm not interested in, and don't care to ever see again:
1) Charlie & his heroin. Charlie and his Driveshaft. Charlie and Claire. Charlie being ambiguous. Charlie being a prat. Charlie.
2) Any backstory that doesn't directly involve matters on the island. I don't care if you have a great back story about Sawyer conning someone that parallels him being a dick on the island. I don't care if Jack's fifteenth flashback deals with the time his father cheated him during a game of Battleship. I don't care that Kate robbed Fort Knox, only to give the gold to her dead boyfriend's favorite charity. The flashback plot device is exhausted. Season Two is the Season of the Flashback. It's done. Focus on the here and now. And, if focusing on the island is too much trouble or hard work because you don't want to reveal all your plot secrets, then go back to daytime soaps and let real writers give us some drama and intrigue. You suck.
3) Claire. Really. Kill her. Done.
4) Michael screaming: "WALT!! WAAAALLLTTT!!!"
5) Jeph Loeb
That's my take. Anyone else?
