The Deep State is made up of influential people in both parties, and transcends the power of either party. Its goals are primarily globalist, but even above that is enriching themselves. In Hillary Clinton they found their perfect candidate, the most corrupt and buyable candidate ever offered, making her their perfect vehicle of choice. And conversely, Trump is a threat to them because he is the most dedicated to breaking up their power structure, and is the least pliable to their control. That is why they want to destroy him.
I didn't see anything in the quoted Politico piece to contradict that.
It DOESN'T break down to strictly Democrat/Republican. Clearly, there is a lot of Establishment Republican resistance to Trump. And going back to Boehner's period as House Speaker, it was visible (even in Boehner's own words) that a rather large faction of Republicans favored Hillary over Trump (i.e., the "Deep State" by any other name.)
Liberals who bemoan discrimination, intolerance, restraint of Constitutional freedoms, and promotion of hatred toward various abberant minorities, have absolutely no problem with discriminating against, being intolerant of, restricting Constitutional freedoms of, and directing hate-filled scapegoat rhetoric against conservatives.
EXACTLY what they accuse Republicans/conservatives of doing, is EXACTLY what liberals/Democrats do themselves, to those who oppose their beliefs.